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Top 10 Medical Innovations for 2014


Which are the up-and-coming technologies and which will have the biggest impact on healthcare in 2014?

Cleveland Clinic's culture of innovation naturally fosters a good deal of discussion about new "game changing" technologies and which ones will have the greatest impact each year. The passion of our clinicians and researchers for getting the best care for patients drives a continuous dialogue on what state-of-the art medical technologies are just over the horizon.

This book was developed to share outside Cleveland Clinic what our clinical leaders are saying to each other and what innovations they feel will help shape healthcare over the next 12 months.


#1 Retinal Prosthesis

In a healthy eye, the rods and cones of the retina are specialized cells that convert light into tiny electrochemical impulses that are sent via the optic nerve into the brain, where they are decoded into images. However, if these delicate photoreceptors are ever damaged, the initial step in the process is disrupted and the visual system cannot transform light into images, leading to blindness...

#1 Retinal Prosthesis

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#2 Genome-Guided Solid Tumor Diagnostics

Too often, men and women hear the words "prostate cancer," "breast cancer," and "colorectal cancer" from their doctors and they immediately think the worst. Many times the aggressive therapies are unnecessary that are offered or demanded. However, there are now genomic-based tests that can make these treatment decisions much easier and more reliable.

#2 Genome-Guided Solid Tumor Diagnostics

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#3 Responsive Neurostimulator for Intractable Epilepsy

Epilepsy is a neurological condition that produces seizures—brief disturbances in the normal electrical activity of the brain—that affect various mental and physical functions. Seizures happen when clusters of nerve cells in the brain signal abnormally, which may briefly alter a person’s consciousness or movements. When a person has two or more unprovoked seizures, he or she is considered to have epilepsy.

#3 Responsive Neurostimulator for Intractable Epilepsy

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#4 New Era in Hepatitis C Treatment

Hepatitis C infection, a common liver disease that affects an estimated four million people in the United States, is transmitted through exposure to infected blood (blood was not screened effectively for hepatitis C until 1992) or sexual contact with an infected person. The majority of people with the ailment don’t realize that they have the disease because of a lack of symptoms.

#4 New Era in Hepatitis C Treatment

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#5 Perioperative Decision Support System

Anesthesia is given to patients to inhibit pain, sedate the body, and also regulate various bodily functions in surgery. Today, there are 51 million hospital surgical procedures performed annually in the United States, most which are not possible without anesthesia. Before the discovery of anesthesia and the first painless surgery in 1842, surgical patients had their pain dulled with opium or copious amounts of alcohol.

#5 Perioperative Decision Support System

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#6 Fecal Microbiota Transplantation

Many hospitalized patients develop hospital-acquired infections, oftentimes due, paradoxically, to broad-spectrum and fluoroquinolone antibiotic therapy used for medical treatment. Antibiotics, which are supposed to kill bacteria, can also increase the odds of some people developing a dangerous and potentially lethal infection from rod-shaped bacteria called Clostridium difficile, or C. diff.

#6 Fecal Microbiota Transplantation

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#7 Relaxin for Acute Heart Failure

Heart failure is a debilitating and potentially life-threatening condition in which the heart is unable to pump enough blood to supply the body. Symptoms of fatigue, shortness of breath, and fluid retention are caused by a weakened or stiffened heart, significantly diminishing its ability to fill normally or effectively distribute blood. According to the American Heart Association, approximately five million people experience heart failure in the United States and more than half a million new cases are diagnosed annually in this country.

#7 Relaxin for Acute Heart Failure

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#8 Computer-Assisted Personalized Sedation Station

A colonoscopy is an exam that lets a gastroenterologist look closely at the inside of the entire colon and rectum for polyps, the small growths that over time can become cancerous. Using a colonoscope, a thin, flexible, hollow, lighted tube that has a tiny video camera on the end, the doctor sends pictures to a TV screen. The exam itself takes about 30 minutes. Patients are usually given light sedation to help them relax and sleep while the procedure is performed.

#8 Computer-Assisted Personalized Sedation Station

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#9 TMAO ASSAY: Novel Biomaker for the Microbiome

There is a global hunt in progress using a variety of cardiovascular fingerprints—scientists call them biomarkers—that have been discovered or created to help identify the initiation, development, and ongoing cascade of damage caused by heart disease.

#9 TMAO ASSAY: Novel Biomaker for the Microbiome

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#10 B-Cell Receptor Pathway Inhibitors

Chemotherapy is a blunt instrument designed to indiscriminately kill rapidly dividing cells in the hope that the cancer cells die more and grow back less than healthy cells. That normal cells are routinely damaged in this destructive procedure accounts for the side effects and toxicity of traditional chemotherapy.

#10 B-Cell Receptor Pathway Inhibitors

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Innovations Spotlight

Education Events

Learn about upcoming education events.

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Spin-Offs

Innovations has facilitated several Cleveland Clinic Spin-Offs over the last decade. Click here to see our current portfolio.

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