Incubator Clients

Abcon Therapeutics is developing an antibody-drug conjugate (ADC) that targets the CD6 cell surface protein on T-cells. In pathogenic conditions, such as T-cell lymphoma and inflammatory conditions, the ADC binds to all T-cells, but the drug (toxin) only affects activated dividing T-cells (i.e. the cancerous ones in T-Cell Lymphoma) so these are killed, and normal inactive T-cells are spared. CD6 is found exclusively on T-cells; thus, the ADC specificity is very good. The Company plans to develop a pipeline of ADCs targeting different types of cancer.

Advanced NanoTherapies (AdvNanoT) aims to take Drug Coated Balloons (DCBs) to the next level with a safe therapeutic option for PAD patients using a drug called Sirolimus.

Aeroscena is the world’s leading resource for essential oil-based clinical inhalation therapy. We focus our expertise on developing evidence-based formulas and cutting-edge diffusion systems that create opportunities for better health.

Bering Health is a digital health start-up that will provide virtual care for low-acuity and low-complexity medical conditions. Individuals will be able to utilize the Company’s digital platform in a convenient setting, such as at home, yet it will still be integrated with an individual’s local provider, thereby maintaining continuous care and up-to-date medical records.

BioChip Labs is a central research laboratory serving the pharmaceutical, biotech and academic communities. The laboratory offers a platform of proprietary, high-complexity assays that are revolutionizing how sickle cell disease and other red cell disorders are managed.

Centerline’s Intra-Operative Positioning System (IOPS) is a platform technology that enhances visualization and navigation across a range of endovascular procedures, while reducing exposure to harmful radiation for patients and physicians.

The Abraham J. & Phyllis Katz Cord Blood Foundation, dba Cleveland Cord Blood Center (CCBC), is a non-profit organization that collects, stores, and distributes stem cell-rich umbilical cord blood units for the treatment of hematologic disorders and regenerative medicine, and for medical research.

Diasome is developing hepatocyte directed vesicle (HDV) nanotechnology to lessen the instances of high and low blood sugar levels in people with diabetes to improve disease management and quality of life.

Global Clinical Connections is involved in total Supply Chain Management. Services range from API (active pharmaceutical ingredient) production through drug manufacturing, packaging, labeling of supplies, and worldwide distribution of Phase I-IV trial supplies to clinical sites.

JanusQ is an early-stage company developing peptide-based therapies that target mitochondrial dysfunction in neurodegenerative diseases. With two lead peptides showing strong efficacy in animal models of Alzheimer’s and Huntington’s Diseases (AD and HD), we are well positioned to drive towards the clinic in pursuit of treatments for these debilitating and life-threatening diseases.

Matrix Medical Devices provides Medical Device Product Development expertise to accelerate its Client’s product development cycle while streamlining post-market surveillance activities.

MED Institute supports consultants, manufacturers, and developers of medical products through the key phases between the start of an idea and making a product available to clinicians and patients.

MediView is refining and further developing that IP to create a revolutionary Extended Reality Surgical Navigation System with initial intended use in the biopsy and ablation of cancerous tumors.

NeuroTherapia is a clinical stage biotechnology company developing novel therapies that decrease the neuroinflammation associated with diseases such as neuropathic pain and Alzheimer’s disease.

NexStep Medical is a company based in France that develops and manufactures in the United States. NexStep Medical has a robust Product Development Pipeline, namely a line extension on current All’InCath®.

ProlifaMetRX has developed a panel of novel technologies to study the only thing that is consistently and completely different between normal and tumor cells, their fundamental growth properties. These technologies have identified not only fundamental differences between normal and tumor cell growth, but pharmaceuticals with the ability to exploit these differences.

Quest Medical Imaging and SPECTRUM 3.0 are the next generation of Fluorescence Guided Surgery. With advanced optical imaging, smart sensors and machine learning software the SPECTRUM 3.0 device provides real time information to assist surgeons in decision making.

The Clinic is a transformative joint venture between Cleveland Clinic and Amwell that brings innovative digital health solutions to a new level with unparalleled ease of use, advanced technologies and powerful outcomes.

XaTek, launched in 2016, is an innovative diagnostic solutions company. The company’s platform technology, ClotChip®, is an in vitro diagnostic global assay for the assessment of any patient’s bleeding profile.

XII Medical is developing a minimally-invasive outpatient technology for the treatment of obstructive sleep apnea (OSA).